Prothrombin Time- Pathology

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The Prothrombin Time (PT)—along with its derived measures of prothrombin ratio (PR) and international normalized ratio (INR)—are assays evaluating the extrinsic pathway of coagulation. This test is also called "ProTime INR" and "PT/INR". They are used to determine the clotting tendency of blood, in the measure of warfarin dosage, liver damage, and vitamin K status. PT measures factors I (Fibrinogen), II (Prothrombin), V (Proaccelerin), VII (Proconvertin), and X (Stuart–Prower Factor). It is used in conjunction with the activated partial thromboplastin time (aPTT) which measures the intrinsic pathway and common pathway.

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